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Published 23:44 22 Jun 2016 BST
Updated 16:57 23 Jun 2016 BST
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Bookies are giving odds of 1/33 on Joshua retaining his belt, while Breazeale is down at 12/1, but you've always got a puncher's chance.
There's a stacked card on too with George Groves facing Martin Murray in a tasty all-British WBA super middleweight title clash.
Chris Eubank Jr returns to the ring for the first time since his controversial British title victory over Nick Blackwell, which left the boxer in a coma. He is overwhelming favourite to beat Tom Doran in the middleweight fight.
Dillian Whyte, who gave Joshua his toughest test to date, will also make his return in a heavyweight fight with Croatian Ivica Bacurin.
Former world champ Nigel Benn's son Conor returns after an impressive pro debut and former Olympian Anthony Agogo is also on the undercard.
The main fight card kicks off at 7pm and the main event will commence around 10pm.
It is being shown on Sky Box Office, so get down to your local pub or blag some mates to order it in, it's going to be fireworks.

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