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Published 09:55 28 Jul 2016 BST
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"It was totally his fault. It was no one else's - he reached for them. He put them in his system. You can't blame anyone else in that situation. That's hard to accept because I loved him so much and was so proud of him."
Mr Ledger also revealed that his daughter, Kate, spoke to her brother the night before his death, urging him to be careful with his medication.
[caption id="attachment_304652" align="aligncenter" width="3000"]"His sister was on the phone to him the night before telling him not to take the prescription medications with the sleeping tablets," Mr Ledger explained.
"[Heath] said: 'Katie, Katie, I'm fine. I know what I'm doing'. He would have had no idea."
“It was a one-off thing. That’s what killed us, because he was warned by his sister the night before: ‘You shouldn’t mix what you’re taking for pnemonia with your ambien’. But most of Heath’s problems were self-induced. “He was a young guy that travelled all the time for work. Even as a two-year-old, he hardly ever slept. He was trying to work and travel and do everything in a short space of time.”When Ledger died, he had just become a father for the first time to a daughter, Matilda, born to his partner, the actress Michelle Williams. [caption id="attachment_304653" align="aligncenter" width="3000"]
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