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Published 21:06 28 Jun 2022 BST
Updated 14:33 29 Jun 2022 BST
A post on her Instagram page on Tuesday night read: "We are deeply saddened to announce the death of Dame Deborah James; the most amazing wife, daughter, sister, mummy."
She passed away peacefully surrounded by her family, the post read.
The post went on to say Dame Deborah was an "inspiration and we are incredibly proud of her and her work".
The presenter went on to say that she felt safe in the knowledge that her children will be surrounded by love after she died. She described her husband of 13 years as the "most wonderful man".
"I know that my kids are going to be more resilient afterward surrounded by love," she said, "my kids are going to be fine.
"But it does not mean that I am not going to miss every chance that I could have had with them."
In an interview with The Sun on May 24, Dame Deborah admitted she was tired because she was scared to go to sleep. She said: "I'm not planning on dying anytime soon but it's just so unpredictable. I'm scared to fall asleep and that's one of the biggest reasons I'm so tired. I am scared to go to sleep." Dame Deborah also took the opportunity to thank her family for going "above and beyond" to take care of her. "What I have seen from them in the last two weeks is true love, deep love," she said, "It's overwhelming. They have all been amazing. I know the pressure on them at the moment is huge, I can't do anything anymore without their help." Despite everything, she was still focused on raising awareness for bowel cancer. "I just think the more awareness I can help raise, the better," she said. And in her final column for The Sun, the mum-of-two said she had prepared memory boxes for her children, Hugo, 14, and Eloise, 12, and bought them "gifts for certain key future birthdays." Ending the column, she said: "I suppose it would be weird to leave my column without saying a few final things: find a life worth enjoying; take risks; love deeply; have no regrets; and always, always have rebellious hope. "And finally, check your poo – it might just save your life." Related links:NHS staff and airports told to prepare for possible UK Ebola outbreak
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